Soft Tissue Sarcoma
Soft Tissue Sarcoma test is a rare form of cancer. Due to its rarity, it is crucial for patients to seek a sarcoma cancer specialist and multi -disciplinary team for treatment. Soft tissue sarcoma can occur in the muscles, fat, blood vessels, tendons, fibrous tissues and synovial tissues (tissues around joints). Soft tissue sarcomas can invade surrounding tissue and can metastasise (spread) to other organs of the body forming a secondary tumour. Secondary tumours are referred to as metastatic soft tissue sarcoma because they are part of the original cancer and are not a new disease. Non- cancerous soft tissue tumours are benign and are rarely life threatening.
In its early stages, soft tissue sarcoma rarely causes any symptoms, as soft tissue is very elastic, the tumours can grow quite large before they are felt. The first symptom is usually a painless lump as the tumour grows and begins to press against nearby nerves and muscles, pain or soreness can occur.
Soft tissue sarcomas can only be diagnosed by a surgical biopsy, which is a procedure which removes tissue from the tumour so that it can be analysed under a microscope.
Soft tissue sarcomas are treated using surgery, radiation therapy, and chemotherapy. Depending on the size, location, extent, and grade (growth rate) of the tumour, a combination of all or some of these treatments may be used. Biological therapy, such as treatment to stimulate the body’s immune system to fight cancer, or molecules that target certain genes expressed by the cancer cells, are also being used for some sarcomas.
*Treatment options should always be discussed with your oncologist and medical team.
Bone sarcomas (bone cancers) are the second large group of sarcoma. There are three types of bone sarcoma: osteosarcoma; Ewing’s sarcoma; and chrondrosarcoma. Bone sarcomas are very likely to be diagnosed in children, and due to the rarity and severity of bone cancer, a bone cancer specialist such as an orthopaedic oncologist, together with a multidisciplinary team, should be consulted in the treatment of the disease.
Bone tumours can be benign (non-cancerous) or malignant (cancerous). Benign bone tumours are rarely life threatening and do not spread within the body, however, they can grow and compress healthy bone tissue.
The most common type of primary bone cancer is osteosarcoma. Because it occurs in growing bones, it is most often found in children. Another type of primary bone cancer is chondrosarcoma which is found in the cartilage. This cancer occurs more often in adults. Ewing’s sarcoma can occur as either a bone sarcoma or a soft tissue sarcoma depending upon the original location in the tumour.
Symptoms and signs
The signs of sarcoma depend on the site where they arise. Patients with bone sarcoma may present with the following symptoms:
- Bone swelling and pain which tends to worsen at night
- Develop fractures after minor trauma as the bone is weakened by the tumour
- A new lump that may not necessarily be painful located anywhere in the body that increases in size, and may grow to a large size over time (patients experiencing soft tissue sarcomas)
X-rays are used to locate a tumour, and if the x-ray suggests a tumour is present than a doctor may require further testing such as a CT scan, Magnetic Resonance Imaging (MRI) or PET scan. Finally, a biopsy must be performed to determine if cancer is present, and is a procedure used to remove sample tissue from the tumour.
A surgeon, usually an orthopaedic oncologist, performs the procedure using a needle or making an incision. During a needle biopsy the surgeon makes a small hole in the bone and removes sample tissue with a small instrument. During an incisional biopsy, the surgeon cuts into the tumour and removes sample tissue. A Pathologist will then study the cells and tissues under a microscope to determine whether the tumour is cancerous.
The treatment of bone cancer depends on the size, location, type and stage of the cancer. Chemotherapy with surgery is often the primary treatment. While amputation of a limb is sometimes necessary, using chemotherapy either before or after surgery has allowed doctors to salvage the limb and improve survival in many cases. Radiation and immunotherapy, and targeted therapies may also present as treatment options.
Why are sarcomas dangerous?
They are hard to diagnose, hard to detect and hard to treat. Biopsy is the only diagnostic tool and surgery often the only curative treatment. Many sarcomas resist current cancer treatments.
TREATMENT OPTIONS SHOULD ALWAYS BE DISCUSSED WITH YOUR ONCOLOGIST AND MEDICAL TEAM
*A DOCTOR SHOULD BE CONSULTED IF THE ABOVE SYMPTOMS OCCUR
*EARLY DIAGNOSIS MEASURABLY IMPROVES SURVIVAL OUTCOMES
*DO NOT IGNORE SYMPTOMS WHICH DO NOT ABATE.